The Glock 45 MOS isn’t your typical handgun—it’s a brilliant hybrid that combines the full-size frame of the Glock 17 with the compact slide of the Glock 19. Designed for professionals but beloved by civilians, this crossover pistol delivers the perfect balance of shootability, capacity, and concealability. What truly elevates the Glock 45 MOS above its peers, though, is its Modular Optic System (MOS), which allows users to easily mount a red dot sight straight onto the slide—no custom milling required.
In today’s world of defensive and competitive shooting, red dot sights have become more than a luxury—they’re a game-changer. A red dot on your Glock 45 MOS means faster target acquisition, better accuracy under pressure, and the ability to stay on target during rapid fire. Whether you’re clearing a room, competing at the range, or simply improving your EDC setup, a quality red dot transforms your pistol into a precision tool.
But with dozens of red dots on the market, finding the right optic for your Glock 45 MOS can be overwhelming. Do you go for the rugged reliability of a Trijicon RMR, or the feature-packed versatility of a Holosun? Do you need night vision compatibility, or is a simple daylight-bright dot enough? How important is battery life, and will it co-witness with your backup iron sights?
This guide answers all those questions—and more. We’ve rounded up the best red dot sights for the Glock 45 MOS, tested and trusted by professionals and everyday carriers alike. Whether you’re on a budget or building a duty-ready setup, the right optic is here waiting for you. Let’s zero in.
5 Best Red Dot Sights for Glock 45 Mos
1) Leupold DeltaPoint Pro Red Dot Sight
Engineered for those who demand professional-grade performance in any environment, the Leupold DeltaPoint Pro (Model #175840) offers an elite optical experience with a durable design that excels in both tactical and recreational applications. This version, finished in a rugged Dark Earth coating, pairs function with a discreet, mission-ready aesthetic, perfect for duty pistols, carbines, or competition handguns.
At the core of this optic is Leupold’s Professional-Grade Red Dot Optical System, delivering industry-leading light transmission, superior glare reduction, and exceptional edge-to-edge clarity. Whether you’re aiming under harsh sunlight or in dim environments, the 2.5 MOA illuminated reticle provides a bright, crisp aiming point that helps you stay on target fast—especially critical in low-light or high-stress scenarios.
This red dot sight features Motion Sensor Technology (MST), a standout energy-saving feature that extends battery life by turning off the reticle after five minutes of inactivity and instantly reactivating it upon detecting movement. That means your optic is always ready—without draining power during idle moments.
Like all Leupold optics, the DeltaPoint Pro is designed, machined, and assembled in the USA, meeting the brand’s legendary durability standards. It’s 100% waterproof, fogproof, and shockproof, making it capable of withstanding the most punishing conditions. Backed by Leupold’s renowned customer support, the DeltaPoint Pro is trusted by military operators, law enforcement officers, and competitive shooters worldwide.
If you need a red dot sight that matches the performance of your firearm, the DeltaPoint Pro Model #175840 delivers confidence with every shot.
Key Specifications
- Model Number: 175840
- Finish: Dark Earth
- Dot Size: 2.5 MOA
- Magnification: 1x (non-magnified)
- Reticle: Illuminated red dot
- Lens System: Leupold Professional-Grade Optical System
- Battery Type: CR2032 (top-loading)
- Battery Life: 300–1600 hours (with MST)
- Motion Sensor Technology (MST): Yes – activates with movement, sleeps after 5 mins
- Brightness Settings: 8 manual levels
- Housing Material: Aircraft-grade aluminum
- Durability: 100% waterproof, fogproof, shockproof
- Mounting Footprint: Leupold proprietary footprint (adapter plates available)
- Weight: Approx. 1.9 oz (without mount)
- Country of Origin: Made in the USA
Pros
- Exceptional optical clarity and light transmission
- Rugged construction with Dark Earth finish for tactical use
- Motion Sensor Technology saves battery and improves readiness
- Tool-free, top-loading battery compartment
- Made and backed by Leupold in the USA
Cons
- Requires proprietary mounting footprint or adapter
2) Primary Arms SLx 1x23mm Mini Red Dot Reflex Sight
The Primary Arms SLx 1x23mm Mini Red Dot Reflex Sight is a purpose-driven optic designed for shooters who want reliability, convenience, and quick target acquisition in a compact package. Tailored specifically for pistols and optics-ready handguns, this sight is part of Primary Arms’ trusted SLx line—known for rugged quality and dependable performance at an excellent value.
One of its standout features is its compatibility with the Docter/Noblex standard mounting footprint, which is widely used across many modern handguns. While some retailers (including Amazon) may list it as fitting Weaver rails, this is incorrect—the optic is not compatible with Weaver rails. It is, however, now confirmed to fit FN509 handguns, expanding its utility for more pistol platforms.
The SLx features a side-loading CR2032 battery compartment, allowing users to change batteries without removing the optic—a convenience that ensures zero retention and eliminates downtime. Combined with simple push-button controls, this sight is user-friendly and perfect for defensive use, EDC, or range training.
Installation is straightforward when using the correct mounting screws. The optic includes three sets of screws for MOS plates, optic-to-MOS, or optic-to-picatinny adapter setups. However, if you’re using a Doctor/Noblex mount directly on your handgun, you’ll need to use the original screws provided by your firearm manufacturer to avoid fitment issues.
In short, the Primary Arms SLx 1x23mm Mini Red Dot brings proven reliability, intuitive design, and modern compatibility in a budget-friendly package—backed by Primary Arms’ strong reputation in the shooting community.
Key Specifications
- Magnification: 1x
- Dot Size: (Typically 3 MOA – confirm if needed)
- Battery Type: CR2032 (side-loading)
- Controls: Push-button brightness adjustment
- Mounting Footprint: Docter/Noblex standard
- Compatibility: FN509 and other handguns with Docter/Noblex cut
- Included Hardware: 3 screw sets (MOS and picatinny adapter compatibility only)
- Durability: Shock-resistant; designed for daily-use handguns
- Weight: Lightweight design (exact weight varies with mount)
Pros
- Side battery compartment allows battery swaps without removing the sight
- Simple push-button controls for easy operation
- Compatible with a wide range of handguns using Docter/Noblex footprint
- Trusted SLx quality from Primary Arms
- Now confirmed to fit FN509 series pistols
Cons
- Not compatible with Weaver rails (despite incorrect listings)
3) Trijicon RMR Type 2 3.25 MOA Red Dot Sight
The Trijicon RMR Type 2 3.25 MOA Red Dot Sight is the gold standard for rugged micro red dots, trusted by military, law enforcement, and competitive shooters around the world. Built with legendary Trijicon durability, this optic is purpose-engineered to withstand harsh environments, intense recoil, and years of heavy use without compromise.
At the heart of the RMR Type 2 is a crisp 3.25 MOA red dot, the most versatile dot size in the RMR lineup. It’s small enough for precision shots and large enough for fast target acquisition, making it ideal for both defensive carry and competition. Whether mounted on a pistol, carbine, or shotgun, this red dot performs reliably in virtually any shooting application.
What truly sets the RMR apart is its forged aluminum housing, shaped in a patented design that effectively diverts impact stress away from the lens. This rugged construction makes it one of the most durable mini red dot sights available today. It’s also waterproof up to 66 feet, shockproof, and fully sealed against the elements.
The RMR Type 2 features automatic and manual brightness settings, offering intuitive adjustment in any lighting condition. It’s compatible with night vision devices and runs on a single CR2032 battery with extended battery life. With its easy-to-access windage and elevation adjustments and wide field of view, it ensures both speed and precision under pressure.
Trusted by professionals in the most demanding environments, the Trijicon RMR Type 2 is a premium optic built for serious shooters who demand reliability, clarity, and performance from every shot.
Key Specifications
- Model: Trijicon RMR Type 2
- Dot Size: 3.25 MOA
- Magnification: 1x
- Battery Type: CR2032
- Battery Life: Up to 4 years (on setting 4 of 8)
- Brightness Settings: Automatic + 8 manual settings
- Housing Material: Forged aluminum
- Adjustment: 1 MOA per click
- Windage/Elevation Range: ±150 MOA
- Mounting Footprint: RMR footprint (widely supported by MOS pistols and adapters)
- Durability: Waterproof to 66 feet, shockproof, fogproof
- Night Vision Compatible: Yes
- Weight: Approx. 1.2 oz (without mount)
Pros
- Extremely durable forged aluminum housing
- Crisp 3.25 MOA dot balances speed and precision
- Auto and manual brightness settings, NV compatible
- Long battery life and proven reliability
- Industry-standard footprint for broad compatibility
Cons
- Premium price point
4) Holosun HS507C-X2 Reflex Red Dot Sight
The Holosun HS507C-X2 Reflex Red Dot Sight is a high-performance optic built for serious pistol shooters who demand reliability, adaptability, and cutting-edge technology. Designed with concealed carriers, tactical professionals, and competition shooters in mind, this sight offers a robust feature set that punches well above its price point. At the core of its appeal is a versatile Multi-Reticle System, a long-lasting green Super LED, and advanced battery-saving features like Shake Awake and Solar Failsafe. Combined with a rugged aluminum housing and intuitive controls, the HS507C-X2 is built to handle both the recoil of full-sized pistols and the demands of real-world environments.
This open reflex sight is not just a tool—it’s a trusted companion for those who count on fast target acquisition and unwavering performance in high-pressure situations. Whether you’re at the range or in a defensive encounter, the HS507C-X2 keeps your aim true and your field of view unobstructed. Its compact footprint makes it ideal for slide-mounted applications, and the included accessories—T10 L Key, CR1632 battery, lens cloth, and user manual—ensure that you’re ready to go right out of the box.
Key Features Explained
Green Super LED with Multi-Reticle System
The HS507C-X2 uses Holosun’s Green Super LED to provide a clear and bright aiming point. You get a Multi-Reticle System that allows you to switch between a precise 2 MOA dot, a 32 MOA circle, or a combination of both. This flexibility lets you adapt your sight picture for speed or precision depending on the shooting scenario.
Shake Awake Technology
Battery life is a crucial factor in any red dot sight, and Holosun addresses it with Shake Awake. When the optic remains idle, it shuts down to conserve power. A slight movement instantly reactivates it, ensuring it’s always ready without manual input. You can set the sleep delay anywhere from 10 minutes to 12 hours, or disable the feature if you prefer.
Solar Failsafe for Backup Power
Even if your battery runs out, the Solar Failsafe keeps your optic powered using ambient light. When in Auto Mode, the brightness of the reticle adjusts automatically based on lighting conditions. Whether you’re in direct sunlight or dim indoor environments, you always have a visible reticle without needing to fiddle with settings.
Lock Mode and Side Battery Tray
Holosun includes a Lock Mode to prevent accidental changes to brightness or reticle settings—a thoughtful feature for duty and concealed carry use. The side-mounted battery tray houses a CR1632 cell and makes battery replacement quick and easy without removing the sight from your pistol.
Specifications
- Reticle: Green 2 MOA Dot & 32 MOA Circle
- Magnification: 1x (Parallax-free)
- Light Wavelength: 540nm
- Brightness Settings: 10 daylight & 2 night vision compatible
- Battery Type: CR1632 (up to 50,000-hour life)
- Power Source: Battery & Solar
- Window Size: 0.63 x 0.91 inches
- Material: 7075 T6 Aluminum Housing
- Finish: Hard Anodized
- Adjustment per Click: 1 MOA
- Windage & Elevation Travel: ±50 MOA
Pros
- Crisp green reticle with three reticle options
- Long-lasting battery with solar backup
- Motion-activated Shake Awake conserves power
- Durable 7075 aluminum construction
- Lock Mode prevents accidental button presses
- Easy-access side battery compartment
- Auto-adjusting brightness in Auto Mode
Cons
- Slightly more expensive than basic red dots, but features justify the cost
Factors to consider when choosing the Best Red Dot Sights for Glock 45 Mos
1. MOS Compatibility
The Glock 45 MOS features a Modular Optic System (MOS) slide, designed to accept a variety of red dot sights using adapter plates. When choosing a red dot, make sure it’s compatible with the Glock MOS system or that you have access to the correct mounting plate. Sights that use the RMR footprint are often ideal for Glock pistols.
2. Durability and Build Quality
A red dot for your Glock 45 MOS must handle recoil and harsh conditions. Look for sights made from strong materials like 7075-T6 aluminum, with a hard-anodized or coated finish. It should also be water-resistant or waterproof and rated to withstand drops, shock, and dust.
3. Reticle Type and Size
Consider the reticle design—common options include 2 MOA dots, 6 MOA dots, and multi-reticle systems (like dot + circle). A smaller dot (2–3 MOA) allows for precise shooting, while a larger dot (5–6 MOA) is quicker to acquire in close quarters. Choose based on your shooting needs—accuracy vs. speed.
4. Battery Life and Power Features
Battery life matters, especially if the sight will be used for carry or duty use. Look for sights offering 10,000 to 50,000+ hours of life. Bonus features like Shake Awake, Auto Shutoff, or Solar Failsafe help conserve power and ensure the dot is always ready when you need it.
Best Red Dot Sights for Glock 45 Mos: FAQs
1. What red dot footprint does the Glock 45 MOS use?
The Glock 45 MOS uses the Modular Optic System (MOS), which supports several red dot footprints via adapter plates. The most commonly compatible footprints include Trijicon RMR, Leupold DPP, and Docter/Noblex. You’ll need to match your red dot sight with the appropriate plate for proper mounting.
2. Do I need to modify my Glock 45 MOS to install a red dot sight?
No. The Glock 45 MOS comes ready for optics. It includes adapter plates that allow you to mount many popular red dot sights without milling or custom slide work. However, you may need aftermarket plates for specific models not supported by the factory set.
3. Can I still use my iron sights with a red dot on my Glock 45 MOS?
Yes, but only if your red dot allows for co-witnessing. This usually requires suppressor-height iron sights that are tall enough to be visible through or around the optic window. Co-witnessing provides a backup aiming system in case your red dot fails.
4. What MOA dot size is best for a Glock 45 MOS red dot?
It depends on your shooting style.
- A 2–3 MOA dot is ideal for precision and longer distances.
- A 5–6 MOA dot is faster to acquire at close range and better for defensive shooting.
Some sights offer a multi-reticle system to let you choose.
Conclusion
Choosing the best red dot sight for your Glock 45 MOS comes down to balancing durability, speed, accuracy, and compatibility. The MOS platform gives you the flexibility to mount a wide range of optics, but selecting the right one ensures you get the most out of your pistol—whether for self-defense, duty, competition, or recreational shooting.
Top red dots like the Holosun 507C, Trijicon RMR, and Leupold DeltaPoint Pro offer rugged construction, long battery life, and intuitive features like shake-awake or auto-brightness. These optics enhance your shooting confidence with faster target acquisition and improved precision. Features such as multi-reticle systems, co-witnessing capability, and side-loading batteries can further improve your user experience.
Ultimately, the best red dot sight for Glock 45 MOS is the one that fits your shooting style, performs reliably under pressure, and integrates seamlessly with your firearm. With the right optic, your Glock 45 MOS becomes a faster, more versatile, and highly effective tool.